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Chemosensory Systems

Group members

 

Prof. Dr. med. Martin Witt  
 

PhD students

Anja Meyer: Die Plastizität des olfaktorischen Systems in einem Mausmodell von Morbus Niemann-Pick Typ C1
Lina-M. Krysewski: "The VNO in Huntington´s disease"
Diana Heimes: Volumetrische Evaluation zentraler olfaktorischer Areale in einem mausbasierten Tiermodell für Morbus Niemann-Pick Typ C1)
Sema Kaya: “The olfactory system in animal models of Multiple Sclerosis”
Lorenzo Brozzetti: University of Verona, Lab member from October 2018-April 2019, defended his PhD thesis successfully at the Univ. of Verona (Neurodegeneration associated-proteins in human olfactoryepithelium: immunocytochemical and biomolecular study in healthy subjectsand patients with synucleinopathies)

 

 

 

News: Anja Meyer (left) and Diana Heimes (right) successfully defended their Doctoral Theses on September 15. Congratulations!!!

Scientific profile

Functional Morphology of Chemosensory Systems

Our group is currently working on the impact of general neurodegeneration on olfactory acuity. We use several animal models that mimic defects occurring in human diseases such as Idiopathic Parkinson´s Syndrome, Huntington´s disease, Multiple Sclerosis or Niemann-Pick disease. Most outcomes are based on immunohistochemical and electron microscopical techniques.

Further interests:

  • Covid-19 and olfaction
  • Distribution pattern of human olfactory epithelium
  • Regenerative potential of the human olfactory system 
  • Human olfactory bulb and central olfactory pathways  
  • Morphology and immunohistochemistry of the human vomeronasal organ
  • Functional morphology of taste buds
  • Histocompatibility of anterior eye chamber stents (glaucoma research)

New Releases

  • Witt M. Anatomy and Development of the Human Gustatory and Olfactory Systems. In: Fritzsch, B. (editor-in-chief) The Senses: A Comprehensive Reference, 2nd Edition, 2021, Academic Press (Elsevier), pp. 85-118,
    ISBN: 978-0-12-805409-3
  • Kirschenbaum D, Imbach LL, Ulrich S, Rushing EJ, Keller E, Reimann RR, Frauenknecht KBM, Lichtblau M, Witt M, Hummel T, Steiger P, Aguzzi A, Frontzek K. "Inflammatory Olfactory Neuropathy in Two Patients with Covid-19." Lancet 396, no. 10245 (Jul 18 2020): 166.
  • Heimes D, Witt M. Morphologie des Riechsystems. Forum HNO. 2020 August; 22:185.


“Full reference list”: here

Methods

• Immunohistochemistry
• Electron microscopy

Cooperation

• Marcus Frank, PhD, Electron microscopic center

• Anja Bräuer, PhD, Anatomy, Molecular Neurobiology, Carl von Ossietzky-Universität Oldenburg

• Thomas Hummel, MD, PhD, Dresden University of Technology Medical School

• Jörg Strotmann, PhD; Physiology, University of Hohenheim

Contact

Prof. Dr. med. Martin Witt 
group leader

Tel.: +49 (0)381 - 494 8435  
Raum: 2.33  
E-Mail: martin.witt{bei}med.uni-rostock.de